If Orion was confused, then Starscream was succeeding. All he had to do was be painfully cryptic and stir up the Autobot's latent inquisitiveness, and the rest should take care of itself. If Orion started asking questions again and poking around where he didn't belong, Megatron would be forced to take action whether he wanted to or not, and Starscream would be proven right. It was a win/win as far as he was concerned.

"Well I'm sure locking yourself in the bowels of the ship certainly isn't helping that situation, now is it?" He says with a pleasant smile.